Hair loss is a very difficult ordeal
for most men to face. Some take it hard and some resign to the thought ‘hair
today gone tomorrow’. But now with Dusteride all your hair can come back
to you again.
Dutasteride or Avodart (brand name)
is an enzyme inhibiting drug. Dutasteride blocks the action of
5-alpha-reductase enzymes which act as a catalyst to convert testosterone into
dihydrotestosterone or DHT. Finasteride, or Propecia (brand name) is also
in the same class of drugs and inhibits the 5-alpha-reductase enzymes, but
where as finestride inhibits only type I isoform of the enzyme Dutasteride
inhibits both type I and type II isoform of the 5-alpha-reductase enzyme.
Dutasteride is a Food and Drug Administration (FDA) approved drug for the treatment of benign prostatic hyperplasia (BPH). It is also prescribed for the Male Pattern
Baldness in men. Some clinical results have indicated that dutasteride at both
0.5 mg and 2.5 mg/day produced a superior hair count and better hair
quality as compared to finasteride 5 mg at weeks 12 and 24.
Male Pattern Baldness and
Dutasteride
Male pattern baldness is the
predominant type of hair loss in men and accounts for 95% of all male hair
loss. It advances in a predictable progression starting with the receding
hair line and thinning of hair at the crown and ending up with a fringe of hair
around the back of the head.
It has been found that among other
genetic and aging factors one thing that is most common in men with Male
Pattern Baldness is an excess of DHT dihydrotestosterone found in the hair
follicles. DHT dihydrotestosterone is a much stronger form of
testosterone. This dihydrotestosterone affects the structure and
functioning of the hair follicle, reducing it in size so much so that it cannot
support a healthy hair, causing gradual and permanaent hair loss known as
Androgenic Alopecia or Male Pattern Baldness. The production of
dihydrotestosterone is made possible with 5-alpha-reductase enzymes.
Dutasteride on inhibiting 5-alpha-reductase enzymes stops the production of
dihydrotestosterone thus eliminating the root cause of Male Pattern
Baldness. Dutasteride not only stops hair loss it even promotes
re-growth! By protecting the hair follicle from dihydrotestoterone Dutateride
promotes healthy recovery of the hair follicle thus enabling it to support a
healthy visible hair.
As yet Food and Drug Administration
(FDA) has not approved Dutasteride for Male Pattern Baldness. However,
GlaxoSmithKline the manufacturers of Dutasteride has completed Phase 2 trials
for its use in treating hair loss.
It should be noted that Dutasteride
is not recommended for women or children. Pregnant women or women who
could get pregnant should not handle this drug as it can cause fetal
deformities in the male fetus.
Dutasteride is a prescription drug
and should be prescribed by your doctor.
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